A seven-year-old boy, who suffered 80% of the skin as a result of bullous epidermolysis, physicians at the Ruhr University in Bochum conducted an experimental treatment, replacing the epidermis with genetically modified skin. Bullous epidermolysis is a serious, incurable disease, as a result of which the skin becomes extremely fragile and vulnerable. Any touch causes the patient painful pain.
In June 2015, the boy was hospitalized with a lesion of 60% of the skin. He had sepsis, fever and doctors could not help him. The only option of salvation is a new experimental therapy.
Initially, researchers took a skin biopsy patient to obtain epidermal stem cells. To correct the existing mutation – the cause of the disease, they were subjected to genetic modification, as a result of which the modified stem cells turned into transgenic skin grafts.
In October, the first transplant was made, as a result of which the boy became much better, followed by several more transplants throughout the body. In total it was possible to restore 80% of the baby’s skin.
In February 2016, operations were completed. Doctors note the successful formation of a new epidermis, healthy skin and even the appearance of the hairline.
This is the first case in the world of such a large-scale transplantation of transgenic skin , which led to positive results. Now, with good reason, we can talk about a unique method of healing an incurable, severe disease.